Fog weather is one of the most important meteorological disasters affecting the traffic safety and management Based on the fog observation data from 68 stations in Zhejiang from 2004 to 2013, the geographic information and the historical traffic loss data, the risk regionalization of the fog disasters on highway in Zhejiang Province is conductedThe risk assessment index sets of fog disasters are established on the basis of the assessment of natural disaster risk theoryThe frequency and duration of fogs are taken as the hazard index, and the traffic accident data rate，the frequency and duration of traffic closing are taken as the vulnerability index, and the passenger and freight volume are taken as the exposure indexThe ArcGIS spatial analysis technique, weighted comprehensive evaluation, and analytic hierarchy process method are used to set up the comprehensive risk evaluation model of fog disasters According to this model, a risk zoning map is compiled The results show that the highway with high risk accounts for 1513% of the total highway length The higher risk sections are mainly located in the sections of Shenjiahu Highway arround the Nanxun and Jiangshan，Hangzhou Bay Ring from Xiaoshan to Yuecheng， the west Hangzhou Ring Highway， ChangTai Highway from Shangyu to Shengzhou, ZhuYong Highway from Zhuji to Pan’an, ShanghaiKunming Highway from Zhuji to Kecheng The research results can provide scientific references for highway management departments of disaster prevention and mitigation plans