The climate comfortability for travel in Lishui is evaluated by using four comprehensive climate indexes: human body comfort meteorological index (BCMI), coldness index (CI), temperature humidity index (THI), and holiday climate index (HCI). The characterization capability of BCMI and HCI are compared and discussed. The results show that Lishui belongs to the firstlevel region of climate comfortability, because there are 8 months with its BCMI grade between 4 and 6 in one whole year. The CI is lower in winter, which means that there is no cold winter. The THI shows that about 60% of regions with its altitude over 600 m have a cool summer, but the other regions with rather high THI. HCI is more comprehensive and objective than BCMI, because HCI considers not only the thermal comfort of climate but also the effects of precipitation and cloud cover on traveling, which is more suitable for daily travel comfort prediction in time scale.