By means of the Flex and AnyMap technology, an emergency response system of meteorological disasters based on the Flex and AnyMap framework is established. Using the secondary development interface of the AnyMap map control of AnyChart Flash chart family, the real time publishing system of Meteorological Disaster Emergency Response for Guangdong Province is developed. The main characteristics can be listed as follows: (1) using the binary data transmission based on the AMF protocol to realize the highefficient exchange of information between service and client ends; (2) using FluorineFx to implement the AMF protocol to raise the development efficiency, and reduce the difficulty in development; (3) using Action Script 3 development language with the platform of the second development interface of the map objects from the AnyChart Flash chat family to get the gorgeous Flex interface. This framework is used in the development of the realtime publishing system of the Meteorological Disaster Emergency Response for Guangdong Province. The system not only has a simple interface and is easy to operate, but also realizes the realtime publishing and timely update of meteorological disaster emergency response information, and improves the level of meteorological disaster emergency response information releasing.