In order to minimize the losses caused by continuous rainfall, the day by day precipitation data of 42 weather stations from late August to middle October of 1970 to 2012, the cotton damage data from continuous rainfall, and the economy data in the same period from the Guangzhong Cotton area of Shaanxi Province are used to conduct risking regionalization, with emphasis on the main disaster (continuous rainfall) in cotton boll opening and mature periods in Guangzhong, based on the ARCGIS platform, so as to make full use of agricultural climatic resources and to avoid unfavorable climates conditions and improve the cap ability of responding to continuous rain disasters. The results show that the highest and medium risk areas of continuous rain in cotton boll opening and mature periods in Guanzhong in Shaanxi include Baoji and the southern Xi’An along the northern foot of Qinling Ranges (Zhouzhi, Huxian, Chang’an and Lantian counties), where are unfavorable for growing cotton in large scale. The low risk regions include Weinan, most parts of Xian Yang, Lintong, Yanliang, and Gaoling counties, where climate conditions are suitable for cotton in boll opening and mature stages.