Taking a Cangzhou chemical project as an example, based on the site investigation and drawing analysis, a lightning hazard assessment is conducted on the current situation of lightning protection for chemical processing devices. The statistical analysis of lightning disaster features, possible influences, lightning hazard analysis, etc. are made by using the lightning data in this project. Referring to the evaluation methods in IEC62305 2, targeting at the project for lightning risk assessment, the risk management measures and suggestions are put forward. The results show that the lightning density is large relatively, and the lightning current amplitude is mainly from 20 to 60 kA. The personal injury risk caused by lightning is mainly due to physical damage caused by flashes to structure, making up about 7050%. The second is the risk caused by flashes happened in the related pipes and lines, making up about 2937%, but mainly in the power system. According to the formal estimation, each structure can meet the basic lightning protection requirements. As for the buildings in this region, the personal injury risk caused by lightning is less than the universally tolerable risk home and abroad. But the original design is short of voltage protection level design. For automation equipment interruption caused by lightning strike to buildings, facilities, pipes and lines, as well as misoperations, may lead to the leakage of toxic substances and flammable accidents, it is still necessary to take further risk control measures. It is important to point out that flammable areas are considered as the third type of lightning protection in the designs of design institutes, as well as the automation control system, is the main sources of lightning risk.