A quantitative assessment is made of the economic loss of main crops, including rice, wheat, rape and tea, resulted from the spring lowtemperature and continuousrain disasters in Xinyang, Henan Province, according to the standard definition of the spring lowtemperature and continuousrain disaster, by means of the related meteorological data from 1971 to 2007. The spring lowtemperature and continuousrain disasters are divided into three levels, based on the durations and harmfulness of disaster inducing factors, such as low temperature in March, “low temperature+continuous rain+low temperaturecontinuousrain” in April, and continuousrain in May. The expected crop yields and the disaster loss rates are calculated with the separation method based on Lagrange interpolation theory. The results show that the spring lowtemperature and continuousrain disasters have different impacts during the different periods in spring on rice, wheat, rape, and tea, most harmful in April and May. It is of great significance to carry out the damage assessment of spring lowtemperature and continuousrain disasters for the disaster prevention/mitigation and decisionmaking of governments at all levels.