The seasonal and annual mean temperature and rainfall from 1953 to 2006 in Meizhou are calculated and analyzed by the means of the linear tendency equation, running mean and R/S (rescaled range analysis) methods. The results indicate that the seasonal and annual mean temperatures in the last 50 years assume increasing trends with the winter temperature having the greatest rate. The annual rainfall and the rainfall in spring, summer and winter also increased, with the summer rainfall having the biggest tendency rate. The R/S results show that temperature and rainfall, have obvious Hurst phenomenon; namely the climatic change in Meizhou has persistence. The H temperature index indicates that the annual and seasonal mean temperatures in Meizhou will continue to assume increasing trends. The temperature increase trend in summer will be more obvious. The H rainfall index indicates that the annul rainfall and rainfall in spring, summer and winter will show an upward tendency while the rainfall in autumn will keep a downward tendency. The increase tendency of spring rainfall will be more obvious.