The communication way, system framework and software realization of the New Generation Mesoscale Automatic Weather Station Network are described. The whole system is based on the CAWS series automatic weather stations, adopting mainly the wireless communication approach supplemented by cable. The system function design was realized though the three-level C/S structure and the B/S structure. Through re-developing the relational database based on the SQL Server 2000 and conducting researches on the meteorological observation methods and datum application with the data collected by automatic weather stations, the new generation mesoscale automatic weather station network becomes a comprehensive system with the capabilities of ground observation, analyzing, predicting, warning, and Web publication combined.